Optimization of signal-to-noise ratio for efficient microarray probe design

Motivation: Target-specific hybridization depends on oligo-probe characteristics that improve hybridization specificity and minimize genome-wide cross-hybridization. Interplay between specific hybridization and genome-wide cross-hybridization has been insufficiently studied, despite its crucial role...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Matveeva, Olga V., Nechipurenko, Yury D., Riabenko, Evgeniy, Ragan, Chikako, Nazipova, Nafisa N., Ogurtsov, Aleksey Y., Shabalina, Svetlana A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
Schlagworte:
ECCB 2016: The 15th European Conference on Computational Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5939967/
https://ncbi.nlm.nih.gov/pubmed/27587674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw451
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