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Comparison of approaches for rational siRNA design leading to a new efficient and transparent method
Current literature describes several methods for the design of efficient siRNAs with 19 perfectly matched base pairs and 2 nt overhangs. Using four independent databases totaling 3336 experimentally verified siRNAs, we compared how well several of these methods predict siRNA cleavage efficiency. Acc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885645/ https://ncbi.nlm.nih.gov/pubmed/17426130 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm088 |
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