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Dual-targeting siRNAs

We have developed an algorithm for the prediction of dual-targeting short interfering RNAs (siRNAs) in which both strands are deliberately designed to separately target different mRNA transcripts with complete complementarity. An advantage of this approach versus the use of two separate duplexes is...

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Bibliografski detalji
Glavni autori: Tiemann, Katrin, Höhn, Britta, Ehsani, Ali, Forman, Stephen J., Rossi, John J., Sætrom, Pål
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2874179/
https://ncbi.nlm.nih.gov/pubmed/20410240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2005710
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