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siRNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines

Cyclin D1 (CCND1) is a known cell cycle regulator whose overexpression is a hallmark of mantle cell lymphoma (MCL). Although molecular techniques have unified the diagnostic approach to MCL, no therapeutic advances have been made to target this particular pathway. The significance of CCND1 in the pa...

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書誌詳細
主要な著者: Tiemann, Katrin, Alluin, Jessica V., Honegger, Anja, Chomchan, Pritsana, Gaur, Shikha, Yun, Yen, Forman, Stephen J., Rossi, John J., Chen, Robert W.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261766/
https://ncbi.nlm.nih.gov/pubmed/21745168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.593272
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