Transvection mediated by the translocated cyclin D1 locus in mantle cell lymphoma

In mantle cell lymphoma (MCL) and some cases of multiple myeloma (MM), cyclin D1 expression is deregulated by chromosome translocations involving the immunoglobulin heavy chain (IgH) locus. To evaluate the mechanisms responsible, gene targeting was used to study long-distance gene regulation. Remark...

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Detalhes bibliográficos
Main Authors: Liu, Hui, Huang, Jing, Wang, Jin, Jiang, Shuguang, Bailey, Alexis S., Goldman, Devorah C., Welcker, Markus, Bedell, Victoria, Slovak, Marilyn L., Clurman, Bruce, Thayer, Mathew, Fleming, William H., Epner, Elliot
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525596/
https://ncbi.nlm.nih.gov/pubmed/18625744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20072102
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