siRNAs targeting cyclin D1 and cyclin D2 enhance the cytotoxicity of chemotherapeutic agents in mantle cell lymphoma cell lines

Cyclin D1 (CCND1) is a known cell cycle regulator whose overexpression is a hallmark of mantle cell lymphoma (MCL). Although molecular techniques have unified the diagnostic approach to MCL, no therapeutic advances have been made to target this particular pathway. The significance of CCND1 in the pa...

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Detaylı Bibliyografya
Asıl Yazarlar: Tiemann, Katrin, Alluin, Jessica V., Honegger, Anja, Chomchan, Pritsana, Gaur, Shikha, Yun, Yen, Forman, Stephen J., Rossi, John J., Chen, Robert W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3261766/
https://ncbi.nlm.nih.gov/pubmed/21745168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.593272
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