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Rational Design of Immunostimulatory siRNAs

Short-interfering RNAs (siRNAs) have engendered much enthusiasm for their ability to silence the expression of specific genes. However, it is now well established that siRNAs, depending on their sequence, can be variably sensed by the innate immune system through recruitment of toll-like receptors 7...

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書誌詳細
主要な著者: Gantier, Michael P, Tong, Stephen, Behlke, Mark A, Irving, Aaron T, Lappas, Martha, Nilsson, Ulrika W, Latz, Eicke, McMillan, Nigel AJ, Williams, Bryan RG
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862527/
https://ncbi.nlm.nih.gov/pubmed/20125126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.4
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