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Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype
Dysregulation of the Wnt signaling pathway is an underlying mechanism in multiple diseases, particularly in cancer. Until recently, identifying agents that target this pathway has been difficult and as a result, no approved drugs exist that specifically target this pathway. We reported previously th...
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| Publicado en: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6688898/ https://ncbi.nlm.nih.gov/pubmed/30551901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.11.022 |
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