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Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy

The Wnt signaling pathway, known for regulating genes critical to normal embryonic development and tissue homeostasis, is dysregulated in many types of cancer. Previously we identified that the anthelmintic drug niclosamide inhibited Wnt signaling by promoting internalization of Wnt receptor Frizzle...

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Bibliografiska uppgifter
I publikationen:Biochem J
Huvudupphovsmän: Wang, Jiangbo, Ren, Xiu-rong, Piao, Hailan, Zhao, Shengli, Osada, Takuya, Premont, Richard T., Mook, Robert A., Morse, Michael A., Lyerly, Herbert Kim, Chen, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6643999/
https://ncbi.nlm.nih.gov/pubmed/30635359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180385
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