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Niclosamide-induced Wnt signaling inhibition in colorectal cancer is mediated by autophagy
The Wnt signaling pathway, known for regulating genes critical to normal embryonic development and tissue homeostasis, is dysregulated in many types of cancer. Previously we identified that the anthelmintic drug niclosamide inhibited Wnt signaling by promoting internalization of Wnt receptor Frizzle...
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| Publicado no: | Biochem J |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6643999/ https://ncbi.nlm.nih.gov/pubmed/30635359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BCJ20180385 |
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