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Structure, Mechanism, and Inhibition of the Zinc-Dependent Histone Deacetylases
Zinc-dependent histone deacetylases (HDACs) regulate the biological function of histone and non-histone proteins through the hydrolysis of acetyllysine side chains to yield free lysine and acetate. Certain HDAC isozymes exhibit alternative catalytic activities, such as polyamine deacetylase or lysin...
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| Publié dans: | Curr Opin Struct Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687579/ https://ncbi.nlm.nih.gov/pubmed/30743180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2019.01.004 |
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