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Functional Relevance of IL-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling
The interleukin 1 (IL-1) receptor family, whose members contain three Ig-like domains (D1-D3) in the extracellular region, is responsible for transmitting pleiotropic signals of IL-1 cytokines. The inter-domain flexibility of IL-1 receptors and its functional roles have not been fully elucidated. In...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6687543/ https://ncbi.nlm.nih.gov/pubmed/31257107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.05.011 |
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