Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein

The major mechanism of antibody-mediated neutralization of the Middle East respiratory syndrome coronavirus (MERS-CoV) involves competition with the cellular receptor dipeptidyl peptidase 4 (DPP4) for binding to the receptor-binding domain (RBD) of the spike (S) glycoprotein. Here, we report a uniqu...

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Опубликовано в: :Cell Rep
Главные авторы: Zhang, Senyan, Zhou, Panpan, Wang, Pengfei, Li, Yangyang, Jiang, Liwei, Jia, Wenxu, Wang, Han, Fan, Angela, Wang, Dongli, Shi, Xuanling, Fang, Xianyang, Hammel, Michal, Wang, Shuying, Wang, Xinquan, Zhang, Linqi
Формат: Artigo
Язык:Inglês
Опубликовано: The Authors. 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7104183/
https://ncbi.nlm.nih.gov/pubmed/29996104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.06.041
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