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Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

The spike glycoprotein (S) of recently identified Middle East respiratory syndrome coronavirus (MERS-CoV) targets the cellular receptor, dipeptidyl peptidase 4 (DPP4). Sequence comparison and modeling analysis have revealed a putative receptor-binding domain (RBD) on the viral spike, which mediates...

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Detalhes bibliográficos
Main Authors: Wang, Nianshuang, Shi, Xuanling, Jiang, Liwei, Zhang, Senyan, Wang, Dongli, Tong, Pei, Guo, Dongxing, Fu, Lili, Cui, Ye, Liu, Xi, Arledge, Kelly C, Chen, Ying-Hua, Zhang, Linqi, Wang, Xinquan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731569/
https://ncbi.nlm.nih.gov/pubmed/23835475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.92
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