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Structural Studies of IRF4 Reveal a Flexible Autoinhibitory Region and a Compact Linker Domain
IRF4 is a unique member of the interferon regulatory factor (IRF) family playing critical regulatory roles in immune cell development, regulation of obesity-induced inflammation, and control of thermogenic gene expression. The ability of IRF4 to control diverse transcriptional programs arises from i...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4646024/ https://ncbi.nlm.nih.gov/pubmed/26405037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.678789 |
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