Structural Studies of AAV2 Rep68 Reveal a Partially Structured Linker and Compact Domain Conformation

Adeno-associated virus (AAV) nonstructural proteins Rep78 and Rep68 carry out all DNA transactions that regulate the AAV life cycle. They share two multifunctional domains: an N-terminal origin binding/nicking domain (OBD) from the HUH superfamily and a SF3 helicase domain. A short linker of ~20 ami...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Biochemistry
Main Authors: Musayev, Faik N., Zarate-Perez, Francisco, Bardelli, Martino, Bishop, Clayton, Saniev, Emil F., Linden, R. Michael, Henckaerts, Els, Escalante, Carlos R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636433/
https://ncbi.nlm.nih.gov/pubmed/26314310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00610
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares