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Structural Insights into the Assembly of the Adeno-associated Virus Type 2 Rep68 Protein on the Integration Site AAVS1

Adeno-associated virus (AAV) is the only eukaryotic virus with the property of establishing latency by integrating site-specifically into the human genome. The integration site known as AAVS1 is located in chromosome 19 and contains multiple GCTC repeats that are recognized by the AAV non-structural...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Musayev, Faik N., Zarate-Perez, Francisco, Bishop, Clayton, Burgner, John W., Escalante, Carlos R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4646001/
https://ncbi.nlm.nih.gov/pubmed/26370092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669960
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