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Structures of apo IRF-3 and IRF-7 DNA binding domains: effect of loop L1 on DNA binding
Interferon regulatory factors IRF-3 and IRF-7 are transcription factors essential in the activation of interferon-β (IFN-β) gene in response to viral infections. Although, both proteins recognize the same consensus IRF binding site AANNGAAA, they have distinct DNA binding preferences for sites in vi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167601/ https://ncbi.nlm.nih.gov/pubmed/21596780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr325 |
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