Functional Relevance of IL-1 Receptor Inter-domain Flexibility for Cytokine Binding and Signaling

The interleukin 1 (IL-1) receptor family, whose members contain three Ig-like domains (D1-D3) in the extracellular region, is responsible for transmitting pleiotropic signals of IL-1 cytokines. The inter-domain flexibility of IL-1 receptors and its functional roles have not been fully elucidated. In...

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Bibliografske podrobnosti
izdano v:Structure
Main Authors: Ge, Jiwan, Remesh, Soumya G., Hammel, Michal, Pan, Si, Mahan, Andrew D., Wang, Shuying, Wang, Xinquan
Format: Artigo
Jezik:Inglês
Izdano: 2019
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687543/
https://ncbi.nlm.nih.gov/pubmed/31257107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2019.05.011
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