Dichlorophenyl piperazines, including a recently-approved atypical antipsychotic, are potent inhibitors of DHCR7, the last enzyme in cholesterol biosynthesis

While antipsychotic medications provide important relief from debilitating psychotic symptoms, they also have significant adverse side effects, which might have relevant impact on human health. Several research studies, including ours, have shown that commonly used antipsychotics such as haloperidol...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Toxicol Appl Pharmacol
Hauptverfasser: Genaro-Mattos, Thiago C., Tallman, Keri A., Allen, Luke B., Anderson, Allison, Mirnics, Karoly, Korade, Zeljka, Porter, Ned A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685688/
https://ncbi.nlm.nih.gov/pubmed/29698737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2018.04.029
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge