Vulnerability of DHCR7(+/−) mutation carriers to aripiprazole and trazodone exposure

Smith-Lemli-Opitz syndrome is a recessive disorder caused by mutations in 7-dehydrocholesterol reductase (DHCR)7 with a heterozygous (HET) carrier frequency of 1–3%. A defective DHCR7 causes accumulation of 7-dehydrocholesterol (DHC), which is a highly oxidizable and toxic compound. Recent studies s...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Korade, Zeljka, Genaro-Mattos, Thiago C., Tallman, Keri A., Liu, Wei, Garbett, Krassimira A., Koczok, Katalin, Balogh, Istvan, Mirnics, Karoly, Porter, Ned A.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665669/
https://ncbi.nlm.nih.gov/pubmed/28972118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079475
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados