Vulnerability of DHCR7(+/−) mutation carriers to aripiprazole and trazodone exposure

Smith-Lemli-Opitz syndrome is a recessive disorder caused by mutations in 7-dehydrocholesterol reductase (DHCR)7 with a heterozygous (HET) carrier frequency of 1–3%. A defective DHCR7 causes accumulation of 7-dehydrocholesterol (DHC), which is a highly oxidizable and toxic compound. Recent studies s...

全面介紹

Na minha lista:
書目詳細資料
發表在:J Lipid Res
Main Authors: Korade, Zeljka, Genaro-Mattos, Thiago C., Tallman, Keri A., Liu, Wei, Garbett, Krassimira A., Koczok, Katalin, Balogh, Istvan, Mirnics, Karoly, Porter, Ned A.
格式: Artigo
語言:Inglês
出版: The American Society for Biochemistry and Molecular Biology 2017
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665669/
https://ncbi.nlm.nih.gov/pubmed/28972118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M079475
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍