Therapeutic antibody targeting microtubule-binding domain prevents neuronal internalization of extracellular tau via masking neuron surface proteoglycans

Pathologically altered tau protein is a common denominator of neurodegenerative disorders including Alzheimer’s disease (AD) and other tauopathies. Therefore, promising immunotherapeutic approaches target and eliminate extracellular pathogenic tau species, which are thought to be responsible for see...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Weisová, Petronela, Cehlár, Ondrej, Škrabana, Rostislav, Žilková, Monika, Filipčík, Peter, Kováčech, Branislav, Prčina, Michal, Wojčiaková, Ľubica, Fialová, Ľubica, Smolek, Tomáš, Kontseková, Eva, Žilka, Norbert, Novák, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6685285/
https://ncbi.nlm.nih.gov/pubmed/31391090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-019-0770-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados