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Interferon Regulatory Factor 3 plays a role in macrophage responses to Interferon-γ

IFN-γ produced during viral infections activates the IFN-γ receptor (IFNGR) complex for STAT1 transcriptional activity leading to expression of Interferon Regulatory Factors (IRF). Simultaneous activation of TBK/IKKε via TLR3 during viral infections activates the transcription factor IRF3. Together...

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Detalhes bibliográficos
Publicado no:Immunobiology
Main Authors: Guinn, Zachary P., Petro, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684403/
https://ncbi.nlm.nih.gov/pubmed/31072630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2019.04.004
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