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Interferon Regulatory Factor 3 plays a role in macrophage responses to Interferon-γ
IFN-γ produced during viral infections activates the IFN-γ receptor (IFNGR) complex for STAT1 transcriptional activity leading to expression of Interferon Regulatory Factors (IRF). Simultaneous activation of TBK/IKKε via TLR3 during viral infections activates the transcription factor IRF3. Together...
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| Publicat a: | Immunobiology |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6684403/ https://ncbi.nlm.nih.gov/pubmed/31072630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2019.04.004 |
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