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Interferon Regulatory Factor 3 plays a role in macrophage responses to Interferon-γ

IFN-γ produced during viral infections activates the IFN-γ receptor (IFNGR) complex for STAT1 transcriptional activity leading to expression of Interferon Regulatory Factors (IRF). Simultaneous activation of TBK/IKKε via TLR3 during viral infections activates the transcription factor IRF3. Together...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Immunobiology
Prif Awduron: Guinn, Zachary P., Petro, Thomas M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6684403/
https://ncbi.nlm.nih.gov/pubmed/31072630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imbio.2019.04.004
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