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Activation of IRF3 contributes to IFN-γ and ISG54 expression during the immune responses to B16F10 tumor growth

Interferon Regulatory Factor (IRF-3) has been shown to contribute to immune control of B16 melanoma tumor growth. We have shown previously that IRF-3 has a role in IFN-γ-induced expression of pro-apoptotic interferon stimulated gene 54 (ISG54) in macrophages and IFN-γ in T cells. To investigate the...

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Detalhes bibliográficos
Publicado no:Int Immunopharmacol
Main Authors: Guinn, Zachary, Brown, Deborah M., Petro, Thomas M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5548377/
https://ncbi.nlm.nih.gov/pubmed/28651122
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.intimp.2017.06.016
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