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IRF-1 responsiveness to IFN-γ predicts different cancer immune phenotypes
BACKGROUND: Several lines of evidence suggest a dichotomy between immune active and quiescent cancers, with the former associated with a good prognostic phenotype and better responsiveness to immunotherapy. Central to such dichotomy is the master regulator of the acute inflammatory process interfero...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3708578/ https://ncbi.nlm.nih.gov/pubmed/23807161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2013.335 |
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