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Significant role for IRF3 in both T cell and APC effector functions during T cell responses
Interferon Regulatory Factor (IRF)3 is a crucial transcription factor during innate immune responses. Here we show IRF3 also has a role in adaptive T cell immune responses. Expression of IFN-γ, IL-17, and Granzyme B (GrB) during in vitro T cell responses was impaired when either dendritic cells (DCs...
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| I publikationen: | Cell Immunol |
|---|---|
| Huvudupphovsmän: | , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2016
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5125847/ https://ncbi.nlm.nih.gov/pubmed/27641636 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2016.08.015 |
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