Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy

Off-target toxicity due to the expression of target antigens in normal tissue or TCR cross-reactivity represents a major risk when using T cell receptor (TCR)-engineered T cells for treatment of solid tumours. Due to the inherent cross-reactivity of TCRs it is difficult to accurately predict their t...

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Bibliografiske detaljer
Udgivet i:Cancer Immunol Immunother
Main Authors: Mensali, Nadia, Myhre, Marit Renée, Dillard, Pierre, Pollmann, Sylvie, Gaudernack, Gustav, Kvalheim, Gunnar, Wälchli, Sébastien, Inderberg, Else Marit
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2019
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6682583/
https://ncbi.nlm.nih.gov/pubmed/31214732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02356-2
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