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Preclinical assessment of transiently TCR redirected T cells for solid tumour immunotherapy
Off-target toxicity due to the expression of target antigens in normal tissue or TCR cross-reactivity represents a major risk when using T cell receptor (TCR)-engineered T cells for treatment of solid tumours. Due to the inherent cross-reactivity of TCRs it is difficult to accurately predict their t...
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| Pubblicato in: | Cancer Immunol Immunother |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Berlin Heidelberg
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6682583/ https://ncbi.nlm.nih.gov/pubmed/31214732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-019-02356-2 |
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