Antigen-delivery through invariant chain (CD74) boosts CD8 and CD4 T cell immunity

Eradication of tumors by the immune system relies on the efficient activation of a T-cell response. For many years, the main focus of cancer immunotherapy has been on cytotoxic CD8 T-cell. However, stimulation of CD4 helper T cells is critical for the promotion and maintenance of immune memory, thus...

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Vydáno v:Oncoimmunology
Hlavní autoři: Mensali, Nadia, Grenov, Amalie, Pati, Niladri Bhusan, Dillard, Pierre, Myhre, Marit Renée, Gaudernack, Gustav, Kvalheim, Gunnar, Inderberg, Else Marit, Bakke, Oddmund, Wälchli, Sébastien
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350688/
https://ncbi.nlm.nih.gov/pubmed/30723591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1558663
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