The Humanin Analogue (HNG) Prevents Temozolomide-Induced Male Germ Cell Apoptosis and Other Adverse Effects in Severe Combined Immuno-Deficiency (SCID) Mice Bearing Human Medulloblastoma

Subfertility is a major concern of long-term cancer survivors at the reproductive age. We have previously demonstrated that a potent humanin analogue, HNG, protected chemotherapy-induced apoptosis in germ cells but not cancer cells in a metastatic melanoma allograft model. In this study, we utilized...

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Опубликовано в: :Exp Mol Pathol
Главные авторы: Jia, Yue, Lue, Yanhe, Swerdloff, Ronald S., Lasky, Joseph L., Panosyan, Eduard H., Dai-Ju, Jenny, Wang, Christina
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6680022/
https://ncbi.nlm.nih.gov/pubmed/31085184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2019.104261
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