TRTH-11. EFFICACY OF ASPARAGINASE ERWINIA CHRYSANTHEMI WITH OR WITHOUT TEMOZOLOMIDE AGAINST GLIOMA CELLS AND INTRACRANIAL MOUSE MEDULLOBLASTOMA

BACKGROUND: Anti-metabolites are less myelosuppressive than DNA-damaging drugs used for brain tumors, and can be tested for efficacy and less overlapping toxicity if combined. We studied if anti-leukemia agent Erwinaze (which depletes asparagine and glutamine) has antitumor effect with or without te...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Sanghez, Valentina, Chen, Mengqing, Fen Chou, Tsui-, Iacovino, Michelina, Lin, Henry, Lasky, Joseph, Panosyan, Eduard
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475200/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.223
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