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TRTH-11. EFFICACY OF ASPARAGINASE ERWINIA CHRYSANTHEMI WITH OR WITHOUT TEMOZOLOMIDE AGAINST GLIOMA CELLS AND INTRACRANIAL MOUSE MEDULLOBLASTOMA
BACKGROUND: Anti-metabolites are less myelosuppressive than DNA-damaging drugs used for brain tumors, and can be tested for efficacy and less overlapping toxicity if combined. We studied if anti-leukemia agent Erwinaze (which depletes asparagine and glutamine) has antitumor effect with or without te...
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| Publicat a: | Neuro Oncol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475200/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.223 |
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