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Humanin analogue, HNG, inhibits platelet activation and thrombus formation by stabilizing platelet microtubules

HNG, a highly potent mutant of the anti‐Alzheimer peptide‐humanin, has been shown to protect against ischaemia‐reperfusion (I/R) injury. However, the underlying mechanism related to platelet activation remains unknown. We proposed that HNG has an effect on platelet function and thrombus formation. I...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Ren, Lijie, Li, Qing, You, Tao, Zhao, Xuefei, Xu, Xingshun, Tang, Chaojun, Zhu, Li
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7176859/
https://ncbi.nlm.nih.gov/pubmed/32174022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15151
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