The Potent Humanin Analogue (HNG) Protects Germ Cells and Leucocytes While Enhancing Chemotherapy-Induced Suppression of Cancer Metastases in Male Mice

Humanin is a peptide that is cytoprotective against stresses in many cell types. We investigated whether a potent humanin analogue S14G-humanin (HNG) would protect against chemotherapy-induced damage to normal cells without interfering with the chemotherapy-induced suppression of cancer cells. Young...

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Bibliographic Details
Published in:Endocrinology
Main Authors: Lue, YanHe, Swerdloff, Ronald, Wan, Junxiang, Xiao, Jialin, French, Samuel, Atienza, Vince, Canela, Victor, Bruhn, Kevin W., Stone, Brian, Jia, Yue, Cohen, Pinchas, Wang, Christina
Format: Artigo
Language:Inglês
Published: Endocrine Society 2015
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Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655208/
https://ncbi.nlm.nih.gov/pubmed/26384090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2015-1542
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