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The Effects of Humanin and Its Analogues on Male Germ Cell Apoptosis Induced by Chemotherapeutic Drugs

Human (HN) prevents stress-induced apoptosis in many cells/tissues. In this study we showed that HN ameliorated chemotherapy (Cyclophosphamide, CP and Doxorubicin, DOX)-induced male germ cell apoptosis both ex vivo in seminiferous tubule cultures and in vivo in the testis. HN acts by several putativ...

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Publicado en:Apoptosis
Autores principales: Jia, Yue, Ohanyan, Aikoui, Lue, Yan-He, Swerdloff, Ronald S., Liu, Peter Y., Cohen, Pinchas, Wang, Christina
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351164/
https://ncbi.nlm.nih.gov/pubmed/25666707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-015-1105-5
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