Transient or extended reversal of apixaban anticoagulation by andexanet alfa is equally effective in a porcine polytrauma model()

BACKGROUND: Andexanet alfa (andexanet) reverses the anticoagulant effects of factor Xa inhibitors, but it has not been assessed in clinical studies for apixaban reversal in trauma. This study evaluated andexanet for reversing apixaban anticoagulation in a porcine polytrauma model. METHODS: Oral apix...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Br J Anaesth
Egile Nagusiak: Grottke, Oliver, Braunschweig, Till, Rossaint, Rolf, Akman, Necib, Leeds, Janet M., Conley, Pamela B., Honickel, Markus
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2019
Gaiak:
Critical Care
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6676228/
https://ncbi.nlm.nih.gov/pubmed/31202564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2019.04.059
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