Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model

Lignende værker

• Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model
  af: Honickel, M, et al.
  Udgivet: (2014)
• In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran
  af: Grottke, O, et al.
  Udgivet: (2014)
• Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs
  af: Honickel, M, et al.
  Udgivet: (2014)
• The Renal Elimination Pathways of the Dabigatran Reversal Agent Idarucizumab and its Impact on Dabigatran Elimination
  af: Glund, Stephan, et al.
  Udgivet: (2018)
• Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution
  af: Grottke, Oliver, et al.
  Udgivet: (2019)