Efficacy of idarucizumab, prothrombin complex concentrate (PCC) and activated PCC to reverse the anticoagulatory potential of dabigatran in a porcine polytrauma model

Ítems similars

• Prothrombin complex concentrate restores haemostasis in a dabigatran anticoagulated polytrauma pig model
  per: Honickel, M, et al.
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• In a trauma experimental pig model prothrombin complex concentrates and a specific antidote (idarucizumab) are effective to reverse the anticoagulant effects of dabigatran
  per: Grottke, O, et al.
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• Use of a specific antidote to dabigatran (idarucizumab) reduces blood loss and mortality in dabigatran-induced and trauma-induced bleeding in pigs
  per: Honickel, M, et al.
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• The Renal Elimination Pathways of the Dabigatran Reversal Agent Idarucizumab and its Impact on Dabigatran Elimination
  per: Glund, Stephan, et al.
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• Volume replacement strategies do not impair the binding of dabigatran to idarucizumab: Porcine model of hemodilution
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