Locus Ceruleus Degeneration Promotes Alzheimer Pathogenesis in Amyloid Precursor Protein 23 Transgenic Mice

Locus ceruleus (LC) degeneration and loss of cortical noradrenergic innervation occur early in Alzheimer’s disease (AD). Although this has been known for several decades, the contribution of LC degeneration to AD pathogenesis remains unclear. We induced LC degeneration with N-(2-chloroethyl)-N-ethyl...

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Argitaratua izan da:J Neurosci
Egile Nagusiak: Heneka, Michael T., Ramanathan, Mutiah, Jacobs, Andreas H., Dumitrescu-Ozimek, Lucia, Bilkei-Gorzo, Andras, Debeir, Thomas, Sastre, Magdalena, Galldiks, Norbert, Zimmer, Andreas, Hoehn, Mathias, Heiss, Wolf-Dieter, Klockgether, Thomas, Staufenbiel, Matthias
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2006
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Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675491/
https://ncbi.nlm.nih.gov/pubmed/16452658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4236-05.2006
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