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Lack of Cannabinoid Receptor Type-1 Leads to Enhanced Age-Related Neuronal Loss in the Locus Coeruleus

Our laboratory and others have previously shown that cannabinoid receptor type-1 (CB1r) activity is neuroprotective and a modulator of brain ageing; a genetic disruption of CB1r signaling accelerates brain ageing, whereas the pharmacological stimulation of CB1r activity had the opposite effect. In t...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Gargano, Alessandra, Beins, Eva, Zimmer, Andreas, Bilkei-Gorzo, Andras
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7792602/
https://ncbi.nlm.nih.gov/pubmed/33374940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010005
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