Φορτώνει......
Ataxin-3 Represses Transcription via Chromatin Binding, Interaction with Histone Deacetylase 3, and Histone Deacetylation
Ataxin-3 (AT3), the disease protein in spinocerebellar ataxia type 3 (SCA3), has been associated with the ubiquitin–proteasome system and transcriptional regulation. Here we report that normal AT3 binds to target DNA sequences in specific chromatin regions of the matrix metalloproteinase-2 (MMP-2) g...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Neurosci |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Society for Neuroscience
2006
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6674535/ https://ncbi.nlm.nih.gov/pubmed/17079677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2053-06.2006 |
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