Prostaglandin D(2)-Mediated Microglia/Astrocyte Interaction Enhances Astrogliosis and Demyelination in twitcher

Prostaglandin (PG) D(2) is well known as a mediator of inflammation. Hematopoietic PGD synthase (HPGDS) is responsible for the production of PGD(2) involved in inflammatory responses. Microglial activation and astrogliosis are commonly observed during neuroinflammation, including that which occurs d...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Mohri, Ikuko, Taniike, Masako, Taniguchi, Hidetoshi, Kanekiyo, Takahisa, Aritake, Kosuke, Inui, Takashi, Fukumoto, Noriko, Eguchi, Naomi, Kushi, Atsuko, Sasai, Hitoshi, Kanaoka, Yoshihide, Ozono, Keiichi, Narumiya, Shuh, Suzuki, Kinuko, Urade, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673986/
https://ncbi.nlm.nih.gov/pubmed/16624958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4531-05.2006
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