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Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

The amyloid precursor protein (APP) is critical in the pathogenesis of Alzheimer's disease. The question of its normal biological function in neurons, in which it is predominantly located at synapses, is still unclear. Using autaptic cultures of hippocampal neurons, we demonstrate that hippocam...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Priller, Christina, Bauer, Thomas, Mitteregger, Gerda, Krebs, Bjarne, Kretzschmar, Hans A., Herms, Jochen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673945/
https://ncbi.nlm.nih.gov/pubmed/16822978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1450-06.2006
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