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Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

The amyloid precursor protein (APP) is critical in the pathogenesis of Alzheimer's disease. The question of its normal biological function in neurons, in which it is predominantly located at synapses, is still unclear. Using autaptic cultures of hippocampal neurons, we demonstrate that hippocam...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Priller, Christina, Bauer, Thomas, Mitteregger, Gerda, Krebs, Bjarne, Kretzschmar, Hans A., Herms, Jochen
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673945/
https://ncbi.nlm.nih.gov/pubmed/16822978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1450-06.2006
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