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Synapse Formation and Function Is Modulated by the Amyloid Precursor Protein

The amyloid precursor protein (APP) is critical in the pathogenesis of Alzheimer's disease. The question of its normal biological function in neurons, in which it is predominantly located at synapses, is still unclear. Using autaptic cultures of hippocampal neurons, we demonstrate that hippocam...

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Опубликовано в: :J Neurosci
Главные авторы: Priller, Christina, Bauer, Thomas, Mitteregger, Gerda, Krebs, Bjarne, Kretzschmar, Hans A., Herms, Jochen
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Neuroscience 2006
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673945/
https://ncbi.nlm.nih.gov/pubmed/16822978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1450-06.2006
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