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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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Bibliografski detalji
Izdano u:Front Mol Neurosci
Glavni autori: Cassar, Marlène, Kretzschmar, Doris
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://ncbi.nlm.nih.gov/pubmed/27507933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00061
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