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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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Detalles Bibliográficos
Publicado en:Front Mol Neurosci
Main Authors: Cassar, Marlène, Kretzschmar, Doris
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://ncbi.nlm.nih.gov/pubmed/27507933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00061
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