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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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Bibliografiske detaljer
Udgivet i:Front Mol Neurosci
Main Authors: Cassar, Marlène, Kretzschmar, Doris
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://ncbi.nlm.nih.gov/pubmed/27507933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00061
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