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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Cassar, Marlène, Kretzschmar, Doris
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://ncbi.nlm.nih.gov/pubmed/27507933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00061
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