Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development

Proteolytic processing of the Amyloid Precursor Protein (APP) produces beta-amyloid (Aβ) peptide fragments that accumulate in Alzheimer's Disease (AD), but APP may also regulate multiple aspects of neuronal development, albeit via mechanisms that are not well understood. APP is a member of a fa...

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Pubblicato in:Front Mol Neurosci
Autori principali: Ramaker, Jenna M., Cargill, Robert S., Swanson, Tracy L., Quirindongo, Hanil, Cassar, Marlène, Kretzschmar, Doris, Copenhaver, Philip F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2016
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122739/
https://ncbi.nlm.nih.gov/pubmed/27932950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00130
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