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Amyloid Precursor Proteins Are Dynamically Trafficked and Processed during Neuronal Development
Proteolytic processing of the Amyloid Precursor Protein (APP) produces beta-amyloid (Aβ) peptide fragments that accumulate in Alzheimer's Disease (AD), but APP may also regulate multiple aspects of neuronal development, albeit via mechanisms that are not well understood. APP is a member of a fa...
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| Pubblicato in: | Front Mol Neurosci |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5122739/ https://ncbi.nlm.nih.gov/pubmed/27932950 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00130 |
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