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Amyloid Precursor Protein family as unconventional Go-coupled receptors and the control of neuronal motility

Cleavage of the Amyloid Precursor Protein (APP) generates amyloid peptides that accumulate in Alzheimer Disease (AD), but APP is also upregulated by developing and injured neurons, suggesting that it regulates neuronal motility. APP can also function as a G protein-coupled receptor that signals via...

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Detalles Bibliográficos
Publicado en:Neurogenesis (Austin)
Main Authors: Ramaker, Jenna M., Copenhaver, Philip F.
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345750/
https://ncbi.nlm.nih.gov/pubmed/28321435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23262133.2017.1288510
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