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Analysis of Amyloid Precursor Protein Function in Drosophila melanogaster

The Amyloid precursor protein (APP) has mainly been investigated in connection with its role in Alzheimer’s Disease (AD) due to its cleavage resulting in the production of the Aβ peptides that accumulate in the plaques characteristic for this disease. However, APP is an evolutionary conserved protei...

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書目詳細資料
發表在:Front Mol Neurosci
Main Authors: Cassar, Marlène, Kretzschmar, Doris
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4960247/
https://ncbi.nlm.nih.gov/pubmed/27507933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2016.00061
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