Pharmacological Activation of mGlu4 Metabotropic Glutamate Receptors Inhibits the Growth of Medulloblastomas

Moving from the evidence that activation of type 4 metabotropic glutamate (mGlu4) receptors inhibits proliferation and promotes differentiation of cerebellar granule cell neuroprogenitors, we examined the expression and function of mGlu4 receptors in medulloblastoma cells. mGlu4 receptors were expre...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Iacovelli, Luisa, Arcella, Antonietta, Battaglia, Giuseppe, Pazzaglia, Simonetta, Aronica, Eleonora, Spinsanti, Paola, Caruso, Alessandra, De Smaele, Enrico, Saran, Anna, Gulino, Alberto, D’Onofrio, Mara, Giangaspero, Felice, Nicoletti, Ferdinando
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2006
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673797/
https://ncbi.nlm.nih.gov/pubmed/16899734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2285-06.2006
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